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Is a split-dose regimen of 2 L polyethylene glycol plus ascorbic acid tolerable for colonoscopy in an early morning visit to a comprehensive medical check-up?
- Source :
-
World journal of gastroenterology [World J Gastroenterol] 2017 Feb 14; Vol. 23 (6), pp. 1030-1037. - Publication Year :
- 2017
-
Abstract
- Aim: To evaluate the effectiveness and tolerability of a split-dose 2 L polyethylene glycol (PEG)/ascorbic acid (AA) regimen for healthy examinees who visited for comprehensive medical check-up in the early morning.<br />Methods: From February 2015 to March 2015, examinees of average risk who were scheduled for a colonoscopy in the morning were retrospectively enrolled.<br />Results: The 189 examinees were divided into split-dose and non-split-dose groups. The adequacy of bowel preparation for the split-dose group vs the non-split-dose group was 96.8% vs 85.2%, respectively, P < 0.001, and the compliance of the last meal restriction was 74.6% vs 58.2%, respectively, P < 0.001. The sleep disturbance ( P < 0.001) was more prevalent in the split-dose group, however the willingness to repeat the same preparation method ( P = 0.243) was not different in both groups. The split-dose regimen was the most important factor influencing adequate bowel preparation in multivariate analysis (HR = 10.89, 95%CI: 6.53-18.17, P < 0.001).<br />Conclusion: A split-dose regimen of 2 L PEG/AA for an early morning colonoscopy was more effective and showed better compliance for diet restriction without any difference in satisfaction and discomfort. Introducing a split-dose regimen of 2 L PEG/AA to morning colonoscopy examinees is effective and tolerable in a comprehensive medical check-up setting.<br />Competing Interests: Conflict-of-interest statement: The authors have no conflict of interest.
- Subjects :
- Adult
Ascorbic Acid adverse effects
Cathartics adverse effects
Comprehensive Health Care
Drug Administration Schedule
Female
Humans
Male
Middle Aged
Patient Compliance
Patient Satisfaction
Physical Examination
Polyethylene Glycols adverse effects
Practice Guidelines as Topic
Prospective Studies
Retrospective Studies
Treatment Outcome
Ascorbic Acid administration & dosage
Cathartics administration & dosage
Colonoscopy methods
Polyethylene Glycols administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 2219-2840
- Volume :
- 23
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- World journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 28246476
- Full Text :
- https://doi.org/10.3748/wjg.v23.i6.1030