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Genotyping and Antifungal Susceptibility of Dipodascus capitatus Isolated in a Neonatal Intensive Care Unit of a Sicilian Hospital.
- Source :
-
Advances in experimental medicine and biology [Adv Exp Med Biol] 2017; Vol. 973, pp. 81-88. - Publication Year :
- 2017
-
Abstract
- In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken. The patients were simultaneously hospitalized, and the comparison of the two isolates by two independent molecular typing methods have confirmed clonal dissemination of a single strain of D. capitatus. Antimicrobial susceptibility testing was useful for identifying the appropriated antifungal therapy in micafungin. To our knowledge these are the first described cases of neonatal D. capitatus infection and also the first report of successful treatment by micafungin.
- Subjects :
- Dipodascus genetics
Dipodascus immunology
Female
Genotype
Hospitals statistics & numerical data
Humans
Infant
Infant, Newborn
Intensive Care Units, Neonatal statistics & numerical data
Male
Sicily
Cross Infection microbiology
Dipodascus drug effects
Dipodascus isolation & purification
Mycoses microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 0065-2598
- Volume :
- 973
- Database :
- MEDLINE
- Journal :
- Advances in experimental medicine and biology
- Publication Type :
- Academic Journal
- Accession number :
- 28213808
- Full Text :
- https://doi.org/10.1007/5584_2016_195