Changes in allele frequencies of CSF3R and SETBP1 mutations and evidence of clonal evolution in a chronic neutrophilic leukemia patient treated with ruxolitinib.

Subjects

Subjects :

Antineoplastic Agents therapeutic use
Bone Marrow pathology
Clonal Evolution drug effects
Disease Progression
Humans
Leukemia, Neutrophilic, Chronic pathology
Leukocyte Count
Nitriles
Protein Kinase Inhibitors therapeutic use
Pyrazoles pharmacology
Pyrimidines
Treatment Outcome
Carrier Proteins genetics
Clonal Evolution genetics
Gene Frequency
Leukemia, Neutrophilic, Chronic drug therapy
Leukemia, Neutrophilic, Chronic genetics
Mutation
Nuclear Proteins genetics
Pyrazoles therapeutic use
Receptors, Colony-Stimulating Factor genetics

Details

Language :

English

ISSN :

1592-8721

Volume :

102

Issue :

5

Database :

MEDLINE

Journal :

Haematologica

Publication Type :

Editorial & Opinion

Accession number :

28209656

Full Text :

https://doi.org/10.3324/haematol.2016.163089