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[Reference values of n-propanol elimination].

Authors :
Wehner HD
Schieffer MC
Source :
Beitrage zur gerichtlichen Medizin [Beitr Gerichtl Med] 1989; Vol. 47, pp. 385-9.
Publication Year :
1989

Abstract

Injections of increasing doses of n-propanol provoke blood concentration curves of exponential decays with dose dependent rate constants. The n-propanol-specific clearance is approximately 10 ml/min. It is determined by a Michaelis-Menten-metabolism (max. velocity of metabolizing: approximately 2.5 mg/l min; Michaelis-Menten-constant: approximately 10 mg/l) and is inhibited in the presence of ethanol.

Details

Language :
German
ISSN :
0067-5016
Volume :
47
Database :
MEDLINE
Journal :
Beitrage zur gerichtlichen Medizin
Publication Type :
Academic Journal
Accession number :
2818507