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Register-based study of the incidence, comorbidities and demographics of obsessive-compulsive disorder in specialist healthcare.
- Source :
-
BMC psychiatry [BMC Psychiatry] 2017 Feb 10; Vol. 17 (1), pp. 64. Date of Electronic Publication: 2017 Feb 10. - Publication Year :
- 2017
-
Abstract
- Background: Incidence of obsessive-compulsive disorder (OCD) has been suspected to increase but nationwide epidemiological studies are limited. This study aims to examine sex-specific incidence time trends and characterize psychiatric and neurodevelopmental comorbidities and sociodemographic risk factors of OCD in specialist healthcare in Finland.<br />Methods: A nationwide register-based study using data from four Finnish registers identified 3372 OCD cases and 13,372 matched controls (1:4). Cumulative incidence in subjects born between 1987 and 2001 was estimated at ages of 10, 15, 20 and 23 years. Conditional logistic regression was used to examine the sociodemographic factors.<br />Results: The cumulative incidence of OCD was 0.4% by age 23. Incidence by age 15 among three cohorts increased from 12.4 to 23.7 /10000 live born males and 8.5 to 28.0 /10000 live born females. 73% of the sample had a comorbid condition. Males were significantly more comorbid with psychotic and developmental disorders; females were more comorbid with depressive and anxiety disorders (p <0.001). Higher maternal SES was associated with an increased risk of OCD (OR 1.4; 95% CI 1.1-1.6).<br />Conclusions: These findings suggest that incidence of treated OCD in specialist healthcare has increased. The reason may be increased awareness and rate of referrals but a true increase cannot be ruled out. Further research on risk factors of OCD is warranted.
Details
- Language :
- English
- ISSN :
- 1471-244X
- Volume :
- 17
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 28183286
- Full Text :
- https://doi.org/10.1186/s12888-017-1224-3