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New developments in the medical treatment of endometriosis.
- Source :
-
Fertility and sterility [Fertil Steril] 2017 Mar; Vol. 107 (3), pp. 555-565. Date of Electronic Publication: 2017 Jan 27. - Publication Year :
- 2017
-
Abstract
- Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are surgical and hormonal but have limitations, including the risk of recurrence, side effects, contraceptive action for women who desire pregnancy, and cost. New treatments include gonadotropin-releasing hormone analogues, selective progesterone (or estrogen) receptor modulators, aromatase inhibitors, immunomodulators, and antiangiogenic agents. Further research is needed into central sensitization, local neurogenesis, and the genetics of endometriosis to identify additional treatment targets. A wider range of medical options allows for the possibility of precision health and a more personalized treatment approach for women with endometriosis.<br /> (Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Angiogenesis Inhibitors adverse effects
Animals
Aromatase Inhibitors adverse effects
Contraceptives, Oral, Hormonal adverse effects
Endometriosis diagnosis
Endometriosis physiopathology
Endometrium pathology
Endometrium physiopathology
Female
Humans
Immunologic Factors adverse effects
Treatment Outcome
Angiogenesis Inhibitors therapeutic use
Aromatase Inhibitors therapeutic use
Contraceptives, Oral, Hormonal therapeutic use
Endometriosis drug therapy
Endometrium drug effects
Immunologic Factors therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1556-5653
- Volume :
- 107
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Fertility and sterility
- Publication Type :
- Academic Journal
- Accession number :
- 28139238
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2016.12.025