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[An Elderly Colon Cancer Patient with Multiple Liver Metastases Who Was Successfully Treated Using mFOLFOX6 and sLV5FU2 Chemotherapy - A Case Report].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2016 Nov; Vol. 43 (12), pp. 1535-1537. - Publication Year :
- 2016
-
Abstract
- Curative treatment for unresectable colon cancer is difficult, and therefore, chemotherapy is often administered in an attempt to improve the prognosis. However, the safety andfeasibility of chemotherapy for elderly patients over 80-years-old have not yet been clarified. We report an elderly colon cancer patient with multiple liver metastases who was successfully treatedwith mFOLFOX6 andsLV5 FU2 chemotherapy. The patient was an 83-year-old-man who was referredto our hospital. After performing sigmoidectomy, we administered mFOLFOX6 chemotherapy. After 5 courses, the regimen was changed to sLV5FU2 owing to grade 3 neuropathy. Liver metastases disappearedanda complete response was obtained1 year after chemotherapy administration. Twenty-four courses of sLV5FU2 chemotherapy had been safely performed. Although grade 1 neutropenia developed, no other adverse event was observed. Currently, the patient is alive without recurrence. Chemotherapy for elderly patients is both feasible and safe.
- Subjects :
- Aged, 80 and over
Humans
Liver Neoplasms diagnostic imaging
Liver Neoplasms secondary
Male
Remission Induction
Sigmoid Neoplasms pathology
Sigmoid Neoplasms surgery
Tomography, X-Ray Computed
Treatment Outcome
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Liver Neoplasms drug therapy
Sigmoid Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 43
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 28133048