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[Prognostic Prediction Models for Liver Metastasis of Colorectal Cancer].

Authors :
Kimura R
Miyoshi N
Ohue M
Yasui M
Wada Y
Fujino S
Sugimura K
Tomokuni A
Akita H
Kobayashi S
Takahashi H
Omori T
Fujiwara Y
Yano M
Sakon M
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2016 Nov; Vol. 43 (12), pp. 1485-1486.
Publication Year :
2016

Abstract

We developed a reliable prediction model for colorectal cancer(CRC)patients after surgically curative resection. Using clinicopathological factors, prediction models were constructed for liver metastasis-free survival(LMFS). Between January 2004 and December 2010, 528 CRC patients were investigated. On univariate analysis of clinicopathological factors, the following factors associated with LMFS: pathological tumor invasion, lymph node metastasis, lymphatic invasion, venous invasion, and preoperative serum CEA. Using these factors, a prediction model was constructed using a Cox regression model with a concordance index of 0.824 for LMFS. These individualized prediction models could help clinicians in the treatment of postoperative CRC patients.

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
43
Issue :
12
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
28133031