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Design of a new tracking device for on-line beam range monitor in carbon therapy.

Authors :
Traini G
Battistoni G
Bollella A
Collamati F
De Lucia E
Faccini R
Ferroni F
Frallicciardi PM
Mancini-Terracciano C
Marafini M
Mattei I
Miraglia F
Muraro S
Paramatti R
Piersanti L
Pinci D
Rucinski A
Russomando A
Sarti A
Sciubba A
Senzacqua M
Solfaroli-Camillocci E
Toppi M
Voena C
Patera V
Source :
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2017 Feb; Vol. 34, pp. 18-27. Date of Electronic Publication: 2017 Jan 19.
Publication Year :
2017

Abstract

Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition to the tumor and surrounding tissues. The design of a new tracking device for beam range real-time monitoring in pencil beam carbon ion therapy is presented. The proposed device tracks secondary charged particles produced by beam interactions in the patient tissue and exploits the correlation of the charged particle emission profile with the spatial dose deposition and the Bragg peak position. The detector, currently under construction, uses the information provided by 12 layers of scintillating fibers followed by a plastic scintillator and a pixelated Lutetium Fine Silicate (LFS) crystal calorimeter. An algorithm to account and correct for emission profile distortion due to charged secondaries absorption inside the patient tissue is also proposed. Finally detector reconstruction efficiency for charged particle emission profile is evaluated using a Monte Carlo simulation considering a quasi-realistic case of a non-homogenous phantom.<br /> (Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1724-191X
Volume :
34
Database :
MEDLINE
Journal :
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Publication Type :
Academic Journal
Accession number :
28111101
Full Text :
https://doi.org/10.1016/j.ejmp.2017.01.004