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Clinical management of Candida albicans keratomycosis in a bottlenose dolphin (Tursiops truncatus).
- Source :
-
Veterinary ophthalmology [Vet Ophthalmol] 2018 May; Vol. 21 (3), pp. 298-304. Date of Electronic Publication: 2017 Jan 11. - Publication Year :
- 2018
-
Abstract
- Objective: Corneal ulceration secondary to trauma commonly affects marine mammals, often with opportunistic secondary bacterial or fungal infections. This report characterizes the combined use of auriculopalpebral and ophthalmic nerve blocks, adipose-derived stem cells, and subconjunctival injections for successful treatment of corneal trauma and infection in dolphins.<br />Animal Studied: An 11-year-old, female bottlenose dolphin (Tursiops truncatus) presented with bilateral diffuse corneal opacities, which progressed to keratomycosis caused by Candida albicans.<br />Procedure: Aggressive medical management was employed, including the use of subconjunctival injections of adipose-derived stem cells, plasma, topical and oral antifungals and antibiotics, and anti-inflammatory and pain medications. Anesthetic block of the auriculopalpebral and ophthalmic nerves was employed to evaluate the corneas.<br />Conclusion: Subconjunctival injections were employed over 52 days, followed by topical drops for 5 months. At last evaluation, there was no evidence of blepharospasm bilaterally. Only a faint superficial gray corneal opacity remained OS. A temporal paraxial corneal opacity was present OD, with receding inactive vascularization and a small amount of melanosis temporally.<br /> (© 2017 American College of Veterinary Ophthalmologists.)
- Subjects :
- Animals
Anti-Infective Agents therapeutic use
Anti-Inflammatory Agents therapeutic use
Candidiasis therapy
Corneal Ulcer microbiology
Corneal Ulcer therapy
Eye Infections, Fungal therapy
Female
Nerve Block veterinary
Stem Cell Transplantation veterinary
Bottle-Nosed Dolphin
Candida albicans
Candidiasis veterinary
Corneal Ulcer veterinary
Eye Infections, Fungal veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1463-5224
- Volume :
- 21
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Veterinary ophthalmology
- Publication Type :
- Report
- Accession number :
- 28074638
- Full Text :
- https://doi.org/10.1111/vop.12459