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Disseminated coccidioidomycosis presenting with intramedullary spinal cord abscesses: Management challenges.
- Source :
-
Medical mycology case reports [Med Mycol Case Rep] 2016 Dec 02; Vol. 15, pp. 1-4. Date of Electronic Publication: 2016 Dec 02 (Print Publication: 2017). - Publication Year :
- 2016
-
Abstract
- Coccidioides species are endemic to the southwestern United States and typically cause a mild or asymptomatic primary infection. In some instances, infection can disseminate and involve the central nervous system with meningitis being the most common manifestation. Non-osseous spinal cord involvement is exceedingly rare. We report a case of disseminated coccidioidomycosis in an otherwise healthy 20 year old man with diffuse leptomeningeal enhancement, cerebrospinal fluid findings suggestive of meningitis, and intramedullary spinal cord abscesses. Response to treatment occurred with prolonged systemic liposomal amphotericin B and voriconazole. An extended course of steroids was needed to blunt inflammation.
Details
- Language :
- English
- ISSN :
- 2211-7539
- Volume :
- 15
- Database :
- MEDLINE
- Journal :
- Medical mycology case reports
- Publication Type :
- Academic Journal
- Accession number :
- 28053850
- Full Text :
- https://doi.org/10.1016/j.mmcr.2016.12.001