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CT-guided core needle biopsy of mediastinal nodes through a transpulmonary approach: retrospective analysis of the procedures conducted over six years.
- Source :
-
European radiology [Eur Radiol] 2017 Aug; Vol. 27 (8), pp. 3401-3407. Date of Electronic Publication: 2017 Jan 03. - Publication Year :
- 2017
-
Abstract
- Purpose: To retrospectively evaluate the diagnostic performance and complications of a CT-guided core needle cutting biopsy of mediastinal nodes through a transpulmonary approach.<br />Materials and Methods: From January 2009 to December 2014, we used a coaxial positioning system and an 18G cutting-type biopsy device to perform CT-guided percutaneous transpulmonary needle biopsies of mediastinal nodes for 127 patients. The diagnostic performance, complication rate, influencing factors, distribution of mediastinal nodes and pathological diagnoses were investigated.<br />Results: Among 127 patients, pathologic analyses showed that all of the biopsies were technically successful. The sensitivity, specificity, positive predictive value, and negative predictive value were all 100%. As for complications, the ratios for pneumothorax and hemoptysis were 33.9% and 4.7%, respectively. Multivariate analyses revealed that the distance from the pleura to the target lesion (P = 0.008) and the numbers of visceral pleura injuries (P = 0.006) were the two most significant risk factors for pneumothorax, and that the distance from the pleura to the target lesion (P = 0.004) was the most significant risk factor for hemoptysis.<br />Conclusions: CT-guided core needle cutting biopsy of mediastinal nodes through a transpulmonary approach is a safe and efficient diagnostic method.<br />Key Points: • CT-guided core needle biopsy is an accurate technique for diagnosing mediastinal nodes. • The rates of complications are similar to those for pulmonary lesion biopsy. • Pneumothorax risk factors include distance from pleura to target lesion and number of visceral pleura. • Distance from pleura to target lesion is the risk factor for hemoptysis. • CT-guided core needle biopsy is an important diagnostic method for mediastinal nodes.
- Subjects :
- Adult
Aged
Biopsy, Large-Core Needle adverse effects
Biopsy, Large-Core Needle methods
Biopsy, Needle methods
Female
Hemoptysis etiology
Humans
Image-Guided Biopsy adverse effects
Lung pathology
Lung Neoplasms pathology
Lymph Nodes pathology
Lymphadenopathy diagnostic imaging
Lymphadenopathy pathology
Lymphatic Metastasis diagnostic imaging
Male
Mediastinum diagnostic imaging
Middle Aged
Patient Positioning
Pleura injuries
Pneumothorax etiology
Retrospective Studies
Risk Factors
Sensitivity and Specificity
Tomography, X-Ray Computed adverse effects
Tomography, X-Ray Computed methods
Image-Guided Biopsy methods
Lymphatic Metastasis pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1084
- Volume :
- 27
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- European radiology
- Publication Type :
- Academic Journal
- Accession number :
- 28050696
- Full Text :
- https://doi.org/10.1007/s00330-016-4718-3