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Incorporation of no-carrier added 200,203 Pb and 200,201,202 Tl in calcium alginate and hesperidin incorporated calcium alginate beads.
- Source :
-
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2017 Mar; Vol. 121, pp. 16-21. Date of Electronic Publication: 2016 Dec 18. - Publication Year :
- 2017
-
Abstract
- When radioisotopes are injected to human body, instantly free radicals are generated due to the interaction of ionizing radiation with water and fluids present in the body. The vehicle carrying radionuclides into human body should therefore be designed in a way which could also eliminate or reduce such possibilities. For the first time we have used free radical scavenger hesperidin, a polyphenolic compound having a benzo-γ-pyrone with a benzene ring moiety for extraction of no-carrier added (NCA) <superscript>200,203</superscript> Pb and <superscript>200,201,202</superscript> Tl. We have modified CA beads by incorporation of a polyphenol (hesperidin) (CA-Hes). This tailor made beads were characterized and tested for their efficacy towards extraction of no-carrier-added lead and thallium radioisotopes from 40MeV α particle irradiated Hg <subscript>2</subscript> Cl <subscript>2</subscript> target.<br /> (Copyright © 2016 Elsevier Ltd. All rights reserved.)
- Subjects :
- Alginates administration & dosage
Drug Compounding methods
Glucuronic Acid administration & dosage
Hesperidin administration & dosage
Hexuronic Acids administration & dosage
Humans
Lead Radioisotopes isolation & purification
Lead Radioisotopes therapeutic use
Microscopy, Electron, Scanning
Radionuclide Imaging methods
Radiopharmaceuticals isolation & purification
Radiopharmaceuticals therapeutic use
Thallium Radioisotopes isolation & purification
Thallium Radioisotopes therapeutic use
Lead Radioisotopes administration & dosage
Radiopharmaceuticals administration & dosage
Thallium Radioisotopes administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1872-9800
- Volume :
- 121
- Database :
- MEDLINE
- Journal :
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 28013152
- Full Text :
- https://doi.org/10.1016/j.apradiso.2016.12.022