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Comparing hybrid hyaluronic acid with PRP in end career athletes with degenerative cartilage lesions of the knee.
- Source :
-
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2016 Oct-Dec; Vol. 30 (4 Suppl 1), pp. 17-23. - Publication Year :
- 2016
-
Abstract
- Cartilage lesions are very common causes of chronic knee pain in athletes. Current treatment options consist in conservative strategies, such as viscosupplementation and platelet-rich plasma injections. This randomized controlled trial aims to investigate the effect of intra-articular Hybrid Hyaluronic Acid injections compared to PRP for the treatment of cartilage lesions among athletes at the end of their career. Since March 2015, 48 professional soccer players were randomized into two groups: 24 patients received 3 injections of HHA and 23 patients received 3 intra-articular injections of PRP. All patients achieved a statistically significant clinical improvement from preoperative to postoperative time in both groups. Patients in the HHA group showed a significant superiority compared to PRP group at 3 and 6 months. Intergroup differences decrease gradually until loss of significance at 12 months follow-up. Athletes with chronic degenerative cartilage lesions of the knee responded positively both to HHA and PRP until last follow up.
- Subjects :
- Humans
Hyaluronic Acid administration & dosage
Hyaluronic Acid chemistry
Injections, Intra-Articular
Osteoarthritis, Knee pathology
Treatment Outcome
Athletes
Cartilage drug effects
Cartilage pathology
Hyaluronic Acid pharmacology
Hyaluronic Acid therapeutic use
Osteoarthritis, Knee drug therapy
Platelet-Rich Plasma
Subjects
Details
- Language :
- English
- ISSN :
- 0393-974X
- Volume :
- 30
- Issue :
- 4 Suppl 1
- Database :
- MEDLINE
- Journal :
- Journal of biological regulators and homeostatic agents
- Publication Type :
- Academic Journal
- Accession number :
- 28002896