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Trichodysplasia Spinulosa in a 7-Year-Old Boy Managed Using Physical Extraction of Keratin Spicules.

Authors :
Barton M
Lockhart S
Sidbury R
Wang R
Brandling-Bennett H
Source :
Pediatric dermatology [Pediatr Dermatol] 2017 Mar; Vol. 34 (2), pp. e74-e76. Date of Electronic Publication: 2016 Dec 19.
Publication Year :
2017

Abstract

Trichodysplasia spinulosa (TS) is an uncommon skin disease characterized by a folliculocentric papular eruption and keratin spine formation, classically appearing on the central face and ears. It occurs in immunosuppressed patients and is linked to a viral etiology. Diagnostic tests including polymerase chain reaction (PCR) are available for detection of the TS-associated polyomavirus. Effective treatment options include topical cidofovir and oral valganciclovir. We present a case diagnosed using PCR with skin scrapings and treated using physical extraction of the keratin spicules. Significant improvement was noted, suggesting a safe, cost-effective treatment alternative.<br /> (© 2016 Wiley Periodicals, Inc.)

Details

Language :
English
ISSN :
1525-1470
Volume :
34
Issue :
2
Database :
MEDLINE
Journal :
Pediatric dermatology
Publication Type :
Academic Journal
Accession number :
27990673
Full Text :
https://doi.org/10.1111/pde.13045