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Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action.

Authors :
Jirapinyo P
Thompson CC
Source :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2017 May; Vol. 15 (5), pp. 619-630. Date of Electronic Publication: 2016 Oct 28.
Publication Year :
2017

Abstract

Obesity is a worsening pandemic with numerous related comorbid illnesses. Conservative management including lifestyle modification and medications have limited efficacy. In contradistinction, bariatric surgery is effective, however, with substantial cost and non-negligible morbidity and mortality. As such, a small percentage of eligible patients undergo surgery. Over the past decade, endoscopic bariatric and metabolic therapies have been introduced as a less invasive option for the treatment of obesity and its related comorbid illnesses. This article reviews major endoscopic bariatric and metabolic therapies, their surgical analogues, and proposed mechanisms of action. Clinical trial data for each device also are discussed.<br /> (Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1542-7714
Volume :
15
Issue :
5
Database :
MEDLINE
Journal :
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Publication Type :
Academic Journal
Accession number :
27989851
Full Text :
https://doi.org/10.1016/j.cgh.2016.10.021