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Successful treatment of mature B-cell lymphoma with rituximab-based chemotherapy in a patient with Bloom syndrome.
- Source :
-
Pediatric blood & cancer [Pediatr Blood Cancer] 2017 Jul; Vol. 64 (7). Date of Electronic Publication: 2016 Dec 14. - Publication Year :
- 2017
-
Abstract
- This report presents a case of Bloom syndrome (BS) in a consanguineous Saudi family. The patient, an 11-year-old male with mature B-cell lymphoma, had minimal therapeutic response and significant dose-limiting toxicity with standard chemotherapy treatment. He later responded successfully to a rituximab-based chemotherapy protocol. This case highlights that the rituximab-based chemotherapy protocol is an effective and safe treatment alternative for mature B-cell lymphoma in patients with BS. Further trials are warranted to investigate this modality of treatment.<br /> (© 2016 Wiley Periodicals, Inc.)
Details
- Language :
- English
- ISSN :
- 1545-5017
- Volume :
- 64
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Pediatric blood & cancer
- Publication Type :
- Academic Journal
- Accession number :
- 27966805
- Full Text :
- https://doi.org/10.1002/pbc.26385