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[A randomized controlled trial of preoperative oral immunonutrition in patients undergoing surgery for colorectal cancer: hospital stay and health care costs].
- Source :
-
Cirugia y cirujanos [Cir Cir] 2017 Sep - Oct; Vol. 85 (5), pp. 393-400. Date of Electronic Publication: 2016 Dec 10. - Publication Year :
- 2017
-
Abstract
- Background: The use of enteral formulas with immunonutrients in patients with gastrointestinal malignancies susceptible to surgery can reduce postoperative morbidity, at the expense of reduced infectious complications, with the consequent reduction in hospital stay and health care costs.<br />Material and Methods: Prospective randomized study. 84 patients operated on a scheduled basis for resectable colorectal cancer were recruited. In the group YES IN Impact © Oral was administered for 8 days (3 sachets a day), compared with the NOT IN group who did not receive it.<br />Results: 40.5% (17) patients without immunonutrition suffered infectious complications vs. 33.3% (14) of YES IN. In patients with rectal cancer NOT IN, 50% (8) suffered minor infectious complications (p=.028). In each group (YES IN, NOT IN, colon and rectal cancer) when infectious complications were observed, the variables total hospital stay and costs doubled, with significant differences. These variables showed higher values in the group NOT IN compared with those who received immunonutrition, although these differences were not statistically significant.<br />Conclusions: NOT IN patients suffered infectious complications more frequently than YES IN, with significant results in the subgroup of patients with rectal cancer. The total hospital stay and costs were slightly higher in the group not supplemented, doubling in each category significantly (YES IN, NOT IN, colon and rectal cancer), when infectious complications were observed.<br /> (Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.)
- Subjects :
- Adenocarcinoma complications
Adenocarcinoma economics
Adenocarcinoma immunology
Aged
Aged, 80 and over
Colorectal Neoplasms complications
Colorectal Neoplasms economics
Colorectal Neoplasms immunology
Dietary Proteins administration & dosage
Female
Humans
Length of Stay economics
Length of Stay statistics & numerical data
Male
Middle Aged
Postoperative Complications prevention & control
Preoperative Care economics
Prospective Studies
Protein-Energy Malnutrition complications
Protein-Energy Malnutrition diet therapy
Adenocarcinoma surgery
Colorectal Neoplasms surgery
Enteral Nutrition economics
Health Care Costs statistics & numerical data
Preoperative Care methods
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 2444-054X
- Volume :
- 85
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cirugia y cirujanos
- Publication Type :
- Academic Journal
- Accession number :
- 27955850
- Full Text :
- https://doi.org/10.1016/j.circir.2016.10.029