Back to Search
Start Over
Safety Assessment of Dialkyl Sulfosuccinate Salts as Used in Cosmetics.
- Source :
-
International journal of toxicology [Int J Toxicol] 2016 Nov; Vol. 35 (3 suppl), pp. 34S-46S. - Publication Year :
- 2016
-
Abstract
- The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 8 dialkyl sulfosuccinate salts for use in cosmetics, finding that these ingredients are safe in cosmetics in the present practices of use and concentration when formulated to be nonirritating. The dialkyl sulfosuccinate salts primarily function as surfactants in cosmetics. The Panel reviewed the new and existing available animal and clinical data in making its determination of safety. The Panel found it appropriate to extrapolate the data on diethylhexyl sodium sulfosuccinate to assess the safety of the entire group because all of the diesters are of a similar alkyl chain length, all are symmetrically substituted, and all have similar functions in cosmetic formulations.<br /> (© The Author(s) 2016.)
- Subjects :
- Animals
Cosmetics chemistry
Dioctyl Sulfosuccinic Acid chemistry
Dioctyl Sulfosuccinic Acid pharmacokinetics
Humans
Molecular Structure
Structure-Activity Relationship
Surface-Active Agents chemistry
Surface-Active Agents pharmacokinetics
Toxicity Tests methods
Toxicokinetics
United States
United States Food and Drug Administration
Consumer Product Safety legislation & jurisprudence
Cosmetics standards
Dioctyl Sulfosuccinic Acid toxicity
Surface-Active Agents toxicity
Subjects
Details
- Language :
- English
- ISSN :
- 1092-874X
- Volume :
- 35
- Issue :
- 3 suppl
- Database :
- MEDLINE
- Journal :
- International journal of toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 27913786
- Full Text :
- https://doi.org/10.1177/1091581816673808