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Regulatory Circuits and Bi-directional Signaling between Stem Cells and Their Progeny.

Authors :
Tata PR
Rajagopal J
Source :
Cell stem cell [Cell Stem Cell] 2016 Dec 01; Vol. 19 (6), pp. 686-689.
Publication Year :
2016

Abstract

Feedback signals from daughter cells to stem cells are well studied and known to provide important feedback cues. Emerging evidence shows that stem cells also send feedforward signals to their progeny. Complex circuits involving both negative and positive feedback and feedforward signals likely contribute to robust tissue maintenance and regeneration.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1875-9777
Volume :
19
Issue :
6
Database :
MEDLINE
Journal :
Cell stem cell
Publication Type :
Academic Journal
Accession number :
27912089
Full Text :
https://doi.org/10.1016/j.stem.2016.11.009