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The BALB/c mouse infection model for improving the Haemophilus parasuis serotyping scheme.

Authors :
Yu J
Zhang Y
Du Y
Li J
Huang B
Sun W
Cong X
Peng J
Ren S
Gou L
Shi J
Chen Z
Chen L
Li J
Yang J
Wu J
Wang J
Source :
Research in veterinary science [Res Vet Sci] 2016 Dec; Vol. 109, pp. 166-168. Date of Electronic Publication: 2016 Oct 24.
Publication Year :
2016

Abstract

The use of BALB/c mouse as an alternative model to study Haemophilus parasuis (HPS) infections was evaluated, supplying the serotyping scheme by comparing the pathogenicity of different serovar HPS in pigs and mice challenge using statistical analysis. Results showed that the pathogenicity of different serovar HPS in mouse was consistent with in pigs, proving that this model is a viable alternative to pigs. It provides a convenient methodology for determining the virulence of HPS strains.<br /> (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1532-2661
Volume :
109
Database :
MEDLINE
Journal :
Research in veterinary science
Publication Type :
Academic Journal
Accession number :
27892867
Full Text :
https://doi.org/10.1016/j.rvsc.2016.10.011