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Subdistal Appendages Stabilize the Ups and Downs of Ciliary Life.

Authors :
Galati DF
Mitchell BJ
Pearson CG
Source :
Developmental cell [Dev Cell] 2016 Nov 21; Vol. 39 (4), pp. 387-389.
Publication Year :
2016

Abstract

Centrioles acquire subdistal appendages (sDAPs) during primary cilium formation. In this issue of Developmental Cell, Mazo et al. (2016) demonstrate that sDAPs keep cilia submerged within deep membrane invaginations. When sDAPs and centrosome cohesion are disrupted, cilia surface to the plasma membrane, which may alter mechanical and chemical signal transduction.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1878-1551
Volume :
39
Issue :
4
Database :
MEDLINE
Journal :
Developmental cell
Publication Type :
Academic Journal
Accession number :
27875681
Full Text :
https://doi.org/10.1016/j.devcel.2016.11.006