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In vitro activity of colistin against Stenotrophomonas maltophilia.
- Source :
-
Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2014 Dec; Vol. 2 (4), pp. 316-317. Date of Electronic Publication: 2014 Jun 05. - Publication Year :
- 2014
-
Abstract
- Colistin is one of the few antimicrobials that retains activity against multidrug-resistant Gram-negative bacteria. However, the emergence of colistin resistance has been described recently. The aims of this study were to determine the activity of colistin against isolates of Stenotrophomonas maltophilia. In total, 641 S. maltophilia clinical isolates were obtained from single patients admitted to a university hospital in Buenos Aires city, Argentina, between the years 1996 and 2013. Susceptibility to colistin was determined by the agar dilution method. An increase in colistin resistance from 8% in 1996 to 45% in 2013 was observed, which correlated with a marked increase in colistin consumption of 11.4-fold during the same period.<br /> (Copyright © 2014 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 2213-7173
- Volume :
- 2
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of global antimicrobial resistance
- Publication Type :
- Academic Journal
- Accession number :
- 27873694
- Full Text :
- https://doi.org/10.1016/j.jgar.2014.04.004