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Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 Dec 01; Vol. 52 (98), pp. 14153-14156. - Publication Year :
- 2016
-
Abstract
- To expand the toolbox of fluorescent protein-based voltage indicators, we explored two distinct protein design strategies. Using these design strategies, we created three new voltage indicators: a red intensiometric voltage indicator (tdFlicR Δ110AR), a green/red ratiometric voltage indicator (tdFlicR-VK-ASAP), and a green to red photoconvertible voltage indicator (FlicGR1).
- Subjects :
- Electricity
HeLa Cells
Humans
Photochemical Processes
Luminescent Proteins chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 52
- Issue :
- 98
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 27869275
- Full Text :
- https://doi.org/10.1039/c6cc06810c