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Analysis of adverse events following immunization in Minas Gerais, Brazil, 2011: a cross-sectional study.
- Source :
-
Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil [Epidemiol Serv Saude] 2016 Jan-Mar; Vol. 25 (1), pp. 45-54. - Publication Year :
- 2016
-
Abstract
- Objective: to analyze the main adverse events occurring following immunization in Minas Gerais State, Brazil, in 2011.<br />Methods: this is a cross-sectional study using secondary data from the Brazilian Information System on Adverse Events Following Immunization.<br />Results: 1,449 adverse events were found; more than half occurred in children under one year of age (56.1%; OR=1.39; 95%CI: 1.08;1.78); the highest rates per 100,000 doses administered were found in the Southern Triangle (36.3), Northwest (25.7) and Southern (22.7) areas of the state; tetravalent vaccine had the highest reactogenicity (46.1%) and hypotonic-hyporesponsive episode was the most frequent event (15.9%); events were significantly associated with inactivated vaccines (OR=4.08; 95%CI: 3.51;4.75); most of the reported events were closed as 'undefined' (58.9%).<br />Conclusion: events were found in all regions of Minas Gerais state and were most frequent following administration of inactivated vaccines and among children under one year of age.
- Subjects :
- Adolescent
Adult
Adverse Drug Reaction Reporting Systems
Age Distribution
Brazil
Child
Child, Preschool
Cross-Sectional Studies
Dioxygenases
Female
Histone Demethylases
Humans
Immunization
Immunization Programs
Immunization, Secondary
Infant
Male
Middle Aged
Nuclear Proteins
Sex Distribution
Young Adult
Vaccination adverse effects
Vaccines adverse effects
Subjects
Details
- Language :
- English; Portuguese
- ISSN :
- 2237-9622
- Volume :
- 25
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
- Publication Type :
- Academic Journal
- Accession number :
- 27861677
- Full Text :
- https://doi.org/10.5123/S1679-49742016000100005