Back to Search
Start Over
Variability of Surgical Site Infection With VEPTR at Eight Centers: A Retrospective Cohort Analysis.
- Source :
-
Spine deformity [Spine Deform] 2016 Jan; Vol. 4 (1), pp. 59-64. Date of Electronic Publication: 2015 Dec 23. - Publication Year :
- 2016
-
Abstract
- Study Design: Retrospective review.<br />Objectives: To describe clinical characteristics and infection rates in modern vertical expandable prosthetic titanium rib (VEPTR) surgery.<br />Summary of Background Data: Prior studies have demonstrated infection rates from 10% to 30% with VEPTR surgery.<br />Methods: A retrospective query was done on an institutional review board-approved, multicenter prospectively collected database for patients implanted with VEPTR from 2007 to 2013 at eight sites. This identified 213 patients with appropriate data for analysis. Average follow-up was 4.1 years (range 1.7-6.3). Data collected included a Classification of Early-Onset Scoliosis (C-EOS) diagnosis, American Society of Anesthesiologists Physical Status (ASA-PS), major Cobb angle, construct type, clinical symptoms, and microbiology. The distribution of infection rates across all the study sites was compared. The exact p value was estimated by Monte Carlo simulation.<br />Results: Overall, 18% (38/213) of patients implanted with VEPTR developed infection requiring operative debridement. There were significantly different infection rates among the sites, ranging from 2.9% to 42.9% (p = .029). The average time to infection was 70 days (range 8-236) after the infecting procedure. The majority of infections were due to gram-positive bacteria (80%, 44/55), the most prevalent being methicillin-sensitive Staphylococcus aureus (45%, 25/55). There were 20 patients (53%, 20/38) with either partial or complete implant removal to resolve infection; however, only 3 of 38 (8%) of these resulted in abandonment of VEPTR treatment. There was no difference in infection rate across the primary C-EOS diagnosis categories (p = .21) or based on ASA score (p = .53). After controlling for study site, the odds ratio of an infection following an implant procedure versus an expansion was 2.8 (p = .002). There was no difference in the odds ratio of an infection between the other procedure types (implant, expansion, exchange/revision).<br />Conclusions: There were significant differences in infection rates between sites. The variability in infection rate indicates a need for guided efforts to standardize best practices for infection control in VEPTR surgery.<br />Level of Evidence: III, therapeutic study.<br /> (Copyright © 2016 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 2212-1358
- Volume :
- 4
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Spine deformity
- Publication Type :
- Academic Journal
- Accession number :
- 27852502
- Full Text :
- https://doi.org/10.1016/j.jspd.2015.07.009