Topical treatment of severe corneal ulcers with cyclosporin A.

Authors :: Zierhut M
Thiel HJ
Weidle EG
Waetjen R
Pleyer U
Source :: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 1989; Vol. 227 (1), pp. 30-5.
Publication Year :: 1989
Abstract: Cyclosporin A eye drops were used on six patients to treat corneal ulcers associated with rheumatic diseases, oculomucocutaneous syndrome, and Sjögren's syndrome. Conjunctival excision was additionally carried out in two cases. All ulcers healed rapidly. The mechanism of ulcer formation involving T-lymphocytes is discussed.

Subjects :: Administration, Topical
Adolescent
Aged
Conjunctiva pathology
Corneal Ulcer immunology
Follow-Up Studies
Humans
Male
Middle Aged
Rheumatic Diseases pathology
Corneal Ulcer drug therapy
Cyclosporins therapeutic use

Language :: English
ISSN :: 0721-832X
Volume :: 227
Issue :: 1
Database :: MEDLINE
Journal :: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Publication Type :: Academic Journal
Accession number :: 2784117
Full Text :: https://doi.org/10.1007/BF02169821