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[Sofosbuvir and daclatasvir combination therapy in hemodialysis patient with liver transplantation].

Authors :
Hachicha M
Botta-Fridlund D
Source :
Nephrologie & therapeutique [Nephrol Ther] 2016 Dec; Vol. 12 (7), pp. 536-538. Date of Electronic Publication: 2016 Nov 04.
Publication Year :
2016

Abstract

We report a case of sustained remission of a liver transplant patient infected with hepatitis C virus (HCV) genotype 1 undergoing hemodialysis treatment. Oral treatment regimen of the HCV infection consists of a combination of sofosbuvir 400 mg after each hemodialysis session and daclatasvir 60 mg daily, for a period of 3 months. Laboratory testing indicate that the combination regimen was well-tolerated with no sign of drug-drug interaction. Confirmation of these clinical observations in large clinical studies may help improve morbidity and decrease mortality outcome in patients infected with HCV and undergoing hemodialysis treatment.<br /> (Copyright © 2016 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.)

Details

Language :
French
ISSN :
1872-9177
Volume :
12
Issue :
7
Database :
MEDLINE
Journal :
Nephrologie & therapeutique
Publication Type :
Academic Journal
Accession number :
27825643
Full Text :
https://doi.org/10.1016/j.nephro.2016.05.010