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When Clinical Trial Participation Is Not an Option in the Era of Personalized Medicine: The Case of Two Patients.

Authors :
Verschraegen CF
Rehman H
Pulluri B
DeKay J
Barry M
Folefac E
Dittus K
Holmes C
Sprague J
Ades S
Gibson PC
Source :
Oncology [Oncology] 2017; Vol. 92 (1), pp. 55-60. Date of Electronic Publication: 2016 Nov 08.
Publication Year :
2017

Abstract

The combination of personalized therapy with immunotherapy might lead to rapid complete remission in patients who are too sick to be eligible for clinical trials. We report 2 such extraordinary responders. A discussion on the use and purpose of clinical trials in this new era of very active anticancer drug discovery concludes that a paradigm shift is urgently needed.<br /> (© 2016 S. Karger AG, Basel.)

Details

Language :
English
ISSN :
1423-0232
Volume :
92
Issue :
1
Database :
MEDLINE
Journal :
Oncology
Publication Type :
Academic Journal
Accession number :
27820931
Full Text :
https://doi.org/10.1159/000450712