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Pancreatic serous cystic neoplasms accompanying other pancreatic tumors.
- Source :
-
Human pathology [Hum Pathol] 2017 Feb; Vol. 60, pp. 104-113. Date of Electronic Publication: 2016 Nov 02. - Publication Year :
- 2017
-
Abstract
- Serous cystic neoplasms (SCNs) are benign cystic neoplasms that predominantly occur in the tail of the pancreas in elderly women. It is well known that patients with von Hippel-Lindau syndrome can develop SCNs and neuroendocrine tumors in the pancreas. However, our understanding on SCNs accompanying other pancreatic tumors (SCNAOPTs) is limited. We compared the clinicopathological features of 15 surgically resected SCNAOPTs with 259 conventional SCNs. The prevalence of SCNAOPT was 5%. The SCNAOPTs were significantly smaller than conventional solitary SCNs, and they were more commonly observed in the head of the pancreas, whereas conventional solitary SCNs were more frequently noted in the body and tail. However, no differences were found in terms of sex, patient age, or the gross patterns of the SCNs. Accompanying neoplasms included 7 intraductal papillary mucinous neoplasms, 1 colloid carcinoma arising from intraductal papillary mucinous neoplasm, 6 neuroendocrine tumors, and 1 solid pseudopapillary neoplasm. Four neuroendocrine tumors associated with von Hippel-Lindau syndrome occurred as multiples, whereas 2 neuroendocrine tumors without von Hippel-Lindau syndrome were solitary. In summary, SCNAOPTs comprise 5% of all SCNs and tend to be smaller and located in the head of the pancreas. Common accompanying tumors include intraductal papillary mucinous neoplasms, neuroendocrine tumors, and other neoplasms such as colloid carcinoma and solid pseudopapillary neoplasm.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Biopsy
Female
Humans
Male
Middle Aged
Neoplasms, Cystic, Mucinous, and Serous diagnostic imaging
Neoplasms, Cystic, Mucinous, and Serous surgery
Pancreatic Cyst diagnostic imaging
Pancreatic Cyst surgery
Pancreatic Neoplasms diagnostic imaging
Pancreatic Neoplasms surgery
Predictive Value of Tests
Prognosis
Tomography, X-Ray Computed
Neoplasms, Cystic, Mucinous, and Serous pathology
Pancreatic Cyst pathology
Pancreatic Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8392
- Volume :
- 60
- Database :
- MEDLINE
- Journal :
- Human pathology
- Publication Type :
- Academic Journal
- Accession number :
- 27816717
- Full Text :
- https://doi.org/10.1016/j.humpath.2016.10.011