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Smoking Is Related to Postoperative Pulmonary Complications and Graft Outcomes in Renal Transplant Patients.
- Source :
-
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [Exp Clin Transplant] 2016 Nov; Vol. 14 (Suppl 3), pp. 87-90. - Publication Year :
- 2016
-
Abstract
- Objectives: Renal transplant is an important treatment option for end-stage renal disease. A successful kidney transplant improves the quality of life and reduces the mortality risk compared with maintenance dialysis in patients with end-stage renal disease. Several immunologic and nonimmunologic factors are responsible for graft outcomes in renal transplant patients. Our study was performed to evaluate the role of smoking on postoperative pulmonary complications and graft outcomes in renal transplant patients.<br />Materials and Methods: Our study retrospectively analyzed 1740 patients who had renal transplants between 1987 and 2014 at Baskent University. Patients with smoking data were included in the study. Patient demographic, smoking status, comorbid diseases, postoperative pulmonary complications, graft outcomes, and clinical features were recorded. The relation between postoperative pulmonary complications and risk factors was investigated.<br />Results: Our study included 131 adult renal transplant recipients who had smoking data. The incidence of postoperative pulmonary complications was 16% (21 patients) in the first month after surgery. Smoking history was found in 52 patients (39.7%). There was a statistically significant relationship between the presence of atelectasis and smoking history (P = .004). A positive and statistically significant correlation was detected between atelectasis and pack-years smoking (r = 0.424; P = .001). We evaluated graft rejection within 1 month after transplant regardless of being acute cellular or humoral rejection. The relation between smoking history and graft rejection within 1 month after transplant was significant (P = .011).<br />Conclusions: Renal transplant patients who are smokers have an increased risk for early postoperative pulmonary complications. Furthermore, cigarette smoking contributes to allograft loss in renal transplant patients. Smoking cessation before surgery can reduce the risk of early postoperative complications.
- Subjects :
- Adult
Allografts
Comorbidity
Female
Graft Rejection immunology
Graft Rejection prevention & control
Graft Survival
Hospitals, University
Humans
Immunity, Cellular
Immunity, Humoral
Kidney Failure, Chronic complications
Kidney Failure, Chronic diagnosis
Lung Diseases diagnosis
Lung Diseases prevention & control
Male
Middle Aged
Retrospective Studies
Risk Assessment
Risk Factors
Smoking Cessation
Smoking Prevention
Time Factors
Treatment Outcome
Turkey
Graft Rejection etiology
Kidney Failure, Chronic surgery
Kidney Transplantation adverse effects
Lung Diseases etiology
Smoking adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 2146-8427
- Volume :
- 14
- Issue :
- Suppl 3
- Database :
- MEDLINE
- Journal :
- Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 27805521