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Gene-corrected human Munc13-4-deficient CD8+ T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.
- Source :
-
Blood [Blood] 2016 Dec 15; Vol. 128 (24), pp. 2859-2862. Date of Electronic Publication: 2016 Oct 31. - Publication Year :
- 2016
- Subjects :
- Animals
CD8-Positive T-Lymphocytes pathology
Genetic Therapy
Herpesvirus 4, Human genetics
Humans
Membrane Proteins deficiency
Mice
Mice, SCID
Transduction, Genetic
CD8-Positive T-Lymphocytes immunology
Epstein-Barr Virus Infections genetics
Epstein-Barr Virus Infections immunology
Epstein-Barr Virus Infections pathology
Herpesvirus 4, Human immunology
Lymphohistiocytosis, Hemophagocytic genetics
Lymphohistiocytosis, Hemophagocytic immunology
Lymphohistiocytosis, Hemophagocytic pathology
Lymphoproliferative Disorders genetics
Lymphoproliferative Disorders immunology
Lymphoproliferative Disorders pathology
Lymphoproliferative Disorders virology
Membrane Proteins immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1528-0020
- Volume :
- 128
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Blood
- Publication Type :
- Report
- Accession number :
- 27799161
- Full Text :
- https://doi.org/10.1182/blood-2016-07-729871