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Exercise capacity following a percutaneous endoscopic gastrostomy in a young female with cystic fibrosis: a case report.
- Source :
-
Physiological reports [Physiol Rep] 2016 Aug; Vol. 4 (16). Date of Electronic Publication: 2016 Aug 22. - Publication Year :
- 2016
-
Abstract
- Cystic fibrosis (CF) is a genetic condition affecting the respiratory and gastrointestinal systems, with patients experiencing problems maintaining weight, especially during rapid growth periods such as puberty. The aim of this case report was to monitor the effect of gastrostomy insertion and implementation of overnight supplemental feeding upon clinical outcomes, including body mass index (BMI), lung function (FEV <subscript>1</subscript> ), and exercise-related variables (maximal oxygen uptake [VO <subscript>2max</subscript> ] and ventilatory efficiency [V <subscript>E</subscript> /VO <subscript>2</subscript> ]) in an 11-year-old female with CF Combined incremental and supramaximal exercise testing to exhaustion was performed at four time points: 3 months prior to the procedure (T1), 2 days prior to (T2), 4 months (T3), and 1 year following the procedure (T4). Improvements following gastrostomy insertion were observed at the 1 year follow-up with regards to BMI (+20%); whereas absolute VO <subscript>2max</subscript> remained stable and lung function fluctuated throughout the period of observation. Declines in function with regards to body weight relative VO <subscript>2max</subscript> (-16.3%) and oxygen uptake efficiency (+7.5%) were observed during this period. This case report is the first to consider exercise-related clinical outcomes in assessing the effect of implementing gastrostomy feeding in CF The varied direction and magnitude of the associations between variables shows that further investigations are required.<br /> (© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.)
- Subjects :
- Body Mass Index
Child
Cystic Fibrosis diet therapy
Cystic Fibrosis surgery
Endoscopy methods
Enteral Nutrition methods
Exercise Test methods
Female
Follow-Up Studies
Gastrostomy methods
Humans
Nutrition Disorders etiology
Outcome Assessment, Health Care
Respiratory Function Tests methods
Body Weight physiology
Cystic Fibrosis complications
Endoscopy adverse effects
Enteral Nutrition adverse effects
Exercise physiology
Gastrostomy adverse effects
Nutrition Disorders surgery
Subjects
Details
- Language :
- English
- ISSN :
- 2051-817X
- Volume :
- 4
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Physiological reports
- Publication Type :
- Academic Journal
- Accession number :
- 27796267
- Full Text :
- https://doi.org/10.14814/phy2.12904