Back to Search
Start Over
Evaluation of exposure of health care personnel to ribavirin.
- Source :
-
Journal of toxicology and environmental health [J Toxicol Environ Health] 1989; Vol. 28 (1), pp. 1-12. - Publication Year :
- 1989
-
Abstract
- Reports that ribavirin was teratogenic in animals raised concerns of female health care personnel about possible occupational exposure during the care of infants having respiratory syncytial virus infections. Under simulated operational conditions, experiments were conducted to measure ribavirin residues in room air, in surface wipe samples, and in personal sampling devices worn by volunteers. There was exposure to a dispersible dust, presumably dried ribavirin, deposited inside the croupette or hood and on the bedding. Based on personal sampler data, it was estimated that, in a 12-h shift, the primary health care individual could inhale 2.4-9.1 micrograms ribavirin/kg bw.d. Recommendations to reduce the exposure of staff included the wearing of appropriate surgical gloves and a NIOSH-approved disposable respirator for dusts and mists while attending to the needs of the patients.
- Subjects :
- Air Pollutants, Occupational analysis
Chromatography, High Pressure Liquid
Female
Humans
Respiratory Syncytial Viruses isolation & purification
Respirovirus Infections drug therapy
Respirovirus Infections microbiology
Ribavirin analysis
Ribavirin therapeutic use
Spectrophotometry, Ultraviolet
Air Pollutants, Occupational toxicity
Nursing Staff, Hospital
Ribavirin toxicity
Ribonucleosides toxicity
Subjects
Details
- Language :
- English
- ISSN :
- 0098-4108
- Volume :
- 28
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of toxicology and environmental health
- Publication Type :
- Academic Journal
- Accession number :
- 2778845
- Full Text :
- https://doi.org/10.1080/15287398909531324