Papillophlebitis versus paediatric venous thrombosis. A case with 46C/T polymorphism in the F12 coagulation gene.

Authors :: Gargallo-Benedicto A
Cerdà-Ibáñez M
Olate-Pérez Á
Clemente-Tomás R
Almor Palacios I
Hervás Hernandis JM
Duch-Samper A
Source :: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol] 2017 Jun; Vol. 92 (6), pp. 291-294. Date of Electronic Publication: 2016 Oct 20.
Publication Year :: 2017
Abstract: Clinical Case: An 8 year-old boy with no known diseases, with sudden loss of visual acuity (VA) in the left eye (LE).<br />Examination: VA 1 in right eye, and 0.1 in LE, discrete left relative afferent pupil defect (RAPD). Normal biomicroscopy. Funduscopy: congestive papilla, venous tortuosity, peripapillary haemorrhages with macular oedema in LE. The systemic study only revealed A C46Tpolymorphism in the F12 coagulation gene. He had a VA of 1 and normal funduscopy 8 months later.<br />Discussion: Papillophlebitis is an inflammatory and non-ischaemic central retinal vein occlusion, ophthalmoscopically similar to central retinal vein thrombosis. The systemic study is essential to rule out underlying diseases.<br /> (Copyright © 2016. Publicado por Elsevier España, S.L.U.)

Subjects :: Anticoagulants therapeutic use
Blindness etiology
Child
Diagnosis, Differential
Factor XII Deficiency
Heterozygote
Humans
Male
Phlebitis drug therapy
Phlebitis genetics
Retinal Vasculitis drug therapy
Factor XII genetics
Mutation, Missense
Optic Disk blood supply
Phlebitis diagnosis
Point Mutation
Retinal Vasculitis genetics
Retinal Vein
Venous Thrombosis diagnosis

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