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Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32 P-siRNA within different lung compartments.

Authors :
Lipka J
Semmler-Behnke M
Wenk A
Burkhardt J
Aigner A
Kreyling W
Source :
Data in brief [Data Brief] 2016 Apr 01; Vol. 7, pp. 1175-1178. Date of Electronic Publication: 2016 Apr 01 (Print Publication: 2016).
Publication Year :
2016

Abstract

Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the <superscript>32</superscript> P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in " Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice " (Lipka et al., 2016 [1]).

Details

Language :
English
ISSN :
2352-3409
Volume :
7
Database :
MEDLINE
Journal :
Data in brief
Publication Type :
Academic Journal
Accession number :
27761500
Full Text :
https://doi.org/10.1016/j.dib.2016.03.092