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PKA Has the Gall to Oppose NLRP3.

Authors :
Groß CJ
Groß O
Source :
Immunity [Immunity] 2016 Oct 18; Vol. 45 (4), pp. 707-709.
Publication Year :
2016

Abstract

The involvement of the NLRP3 inflammasome in inflammatory diseases has generated interest in identifying endogenous mechanisms that inhibit NLRP3. In this issue of Immunity, Guo et al. (2016) reveal bile acids as negative regulators of the NLRP3 inflammasome.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)

Subjects

Subjects :
Animals
Humans
Inflammasomes immunology
Inflammasomes metabolism
Inflammation immunology
Inflammation metabolism
Cyclic AMP-Dependent Protein Kinases immunology
Cyclic AMP-Dependent Protein Kinases metabolism
NLR Family, Pyrin Domain-Containing 3 Protein immunology
NLR Family, Pyrin Domain-Containing 3 Protein metabolism

Details

Language :
English
ISSN :
1097-4180
Volume :
45
Issue :
4
Database :
MEDLINE
Journal :
Immunity
Publication Type :
Academic Journal
Accession number :
27760332
Full Text :
https://doi.org/10.1016/j.immuni.2016.09.019
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