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Patients with cervical Ureaplasma Urealyticum and Chlamydia Trachomatis infection undergoing IVF/ICSI-ET: The need for new paradigm.
- Source :
-
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban [J Huazhong Univ Sci Technolog Med Sci] 2016 Oct; Vol. 36 (5), pp. 716-722. Date of Electronic Publication: 2016 Oct 18. - Publication Year :
- 2016
-
Abstract
- Genital tract infections with ureaplasma urealyticum (UU) and chlamydia trachomatis (CT) are the most frequent sexually-transmitted disease worldwide. UU and CT infections are considered to be the leading cause for infertility and adverse pregnancy outcomes. However, little is known about the specific effect of cervical UU and CT infections on the etiology of female infertility, as well as the pregnancy outcomes of the patients undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET). In order to find the association between cervical UU and/or CT infection and pregnancy outcomes, we conducted a retrospective case-control study on the patients undergoing IVF/ICSI-ET with cervical UU and/or CT infection. A total of 2208 patients who received IVF/ICSI-ET were enrolled in this study. Data on the general conditions, pregnancy history and clinical pregnant outcomes were analyzed in terms of the cervical UU and CT detection. Our results revealed that cervical UU and CT infections were the risk factors for ectopic pregnancy and tubal factor-induced infertility. Moreover, the pregnancy rate, abortion rate, ectopic pregnancy rate and premature birth rate in patients with UU and/or CT infections showed no significant difference when compared with the control group. We recommend that cervical UU and CT detection should be an optional item for infertility patients and clinical UU detection should differentiate the subtypes of cervical UU. Positive cervical UU and CT infections should not be taken as strict contraindications for IVF/ICSI-ET.
- Subjects :
- Adult
Chlamydia Infections pathology
Embryo Transfer
Female
Fertilization in Vitro
Humans
Male
Pregnancy
Pregnancy Rate
Premature Birth
Reproductive Tract Infections microbiology
Sperm Injections, Intracytoplasmic methods
Ureaplasma Infections pathology
Chlamydia Infections microbiology
Chlamydia trachomatis pathogenicity
Reproductive Tract Infections physiopathology
Ureaplasma Infections microbiology
Ureaplasma urealyticum pathogenicity
Subjects
Details
- Language :
- English
- ISSN :
- 1993-1352
- Volume :
- 36
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
- Publication Type :
- Academic Journal
- Accession number :
- 27752891
- Full Text :
- https://doi.org/10.1007/s11596-016-1650-3