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Autoimmune estrogen dermatitis in an infertile female.
- Source :
-
Cutaneous and ocular toxicology [Cutan Ocul Toxicol] 2017 Jun; Vol. 36 (2), pp. 195-198. Date of Electronic Publication: 2016 Nov 02. - Publication Year :
- 2017
-
Abstract
- Autoimmune estrogen dermatitis is a cyclical cutaneous eruption that occurs premenstrually and goes to the rapid resolution within a few days of menstrual cycles. The disorder has variable clinical manifestations consisting of macules, papules, vesicles, urticarial lesions, bullae, eczematous plaques, and erythema multiforme-like lesions. Herein, we present a case of a 30-year-old woman with attacks of edema and erosions involving the oral and genital mucosal sites on every first day of her menstruation period. She had also multiple endocrinological problems such as hypotroidism and infertility. To determine the sex hormon sensitivity, intradermal skin tests were performed. Based on her personal history and skin test findings, a diagnosis of autoimmune estrogen dermatitis was made. After the oophorectomy, she was free from the skin and mucosal symptoms. We propose that it is important to suspect the diagnosis of autoimmune estrogen dermatitis in patients who present with recurrent cylic eruptions and it must be kept in mind that these patients might have a concomitant infertility.
- Subjects :
- Adult
Autoimmune Diseases complications
Autoimmune Diseases immunology
Autoimmune Diseases therapy
Biopsy
Dermatitis complications
Dermatitis immunology
Dermatitis therapy
Estrogen Antagonists therapeutic use
Female
Gonadotropin-Releasing Hormone analogs & derivatives
Humans
Leuprolide adverse effects
Leuprolide therapeutic use
Mouth Mucosa immunology
Ovariectomy
Pain etiology
Pruritus etiology
Skin immunology
Skin pathology
Skin Tests
Tamoxifen therapeutic use
Autoimmune Diseases diagnosis
Dermatitis diagnosis
Estrogens immunology
Hypothyroidism complications
Infertility complications
Menstrual Cycle immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1556-9535
- Volume :
- 36
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cutaneous and ocular toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 27723997
- Full Text :
- https://doi.org/10.1080/15569527.2016.1245197