Ecological effects on arbovirus-mosquito cycles of transmission.

Authors :: Tabachnick WJ
Source :: Current opinion in virology [Curr Opin Virol] 2016 Dec; Vol. 21, pp. 124-131. Date of Electronic Publication: 2016 Sep 28.
Publication Year :: 2016
Abstract: Mosquitoes transmit many viruses to a variety of hosts. Cycles of mosquito borne arbovirus transmission are the result of complex interactions between the mosquito, the arbovirus and the host that are influenced by genetic variations in a variety of traits in each that are all influenced by many environmental factors. R <subscript>0</subscript> , the basic reproduction number or mean number of individuals infected from a single infected individual, is a measure of mosquito borne arbovirus transmission. Understanding the causes for the distribution of R <subscript>0</subscript> in any transmission cycle is a daunting challenge due to the lack of information on the genetic and environmental variances that influence R <subscript>0</subscript> . Information about the major factors influencing R <subscript>0</subscript> for specific transmission cycles is essential to develop efficient and effective strategies to reduce transmission in different cycles and locations.<br /> (Copyright Â© 2016 Elsevier B.V. All rights reserved.)