Anti-PD1-Induced Pneumonitis: Capturing the Hidden Enemy.

Authors :: Castanon E
Source :: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2016 Dec 15; Vol. 22 (24), pp. 5956-5958. Date of Electronic Publication: 2016 Sep 28.
Publication Year :: 2016
Abstract: Anti-PD1 antibodies have led to a therapeutic shift in cancer treatment. Although classically described as "well tolerated," these drugs can lead to severe immune-related adverse events. Using CT scan imaging, Nishino and colleagues describe different radiologic patterns and their possible relation to severity of several cases of anti-PD1-induced pneumonitis. Clin Cancer Res; 22(24); 5956-8. ©2016 AACRSee related article by Nishino et al., p. 6051.<br /> (©2016 American Association for Cancer Research.)

Subjects :: Antibodies, Monoclonal therapeutic use
Humans
Neoplasms drug therapy
Neoplasms metabolism
Pneumonia metabolism
Antibodies, Monoclonal adverse effects
Pneumonia chemically induced
Programmed Cell Death 1 Receptor metabolism

Language :: English
ISSN :: 1557-3265
Volume :: 22
Issue :: 24
Database :: MEDLINE
Journal :: Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Type :: Academic Journal
Accession number :: 27683178
Full Text :: https://doi.org/10.1158/1078-0432.CCR-16-2033