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A laparoscopic technique of partial hepatectomy in the rat.
- Source :
-
The Journal of surgical research [J Surg Res] 2016 Oct; Vol. 205 (2), pp. 286-291. Date of Electronic Publication: 2016 Jul 05. - Publication Year :
- 2016
-
Abstract
- Background: Laparoscopic partial hepatectomy is an increasingly applied technique in the treatment of liver tumors and in living donor transplantation. There is a need for establishing an animal model that would facilitate experimental research on the technique. The aim of the present study was to describe a safe and efficient laparoscopic technique of 70% partial hepatectomy in the rat.<br />Materials and Methods: Twenty-four male Wistar rats underwent either laparoscopic (group LAP-HEP) or open resection of the median and left lateral hepatic lobes (group HEP). In group LAP-HEP, a 5-mm Hg pneumoperitoneum was established. Three 5-mm trocars were introduced in the abdominal cavity. A self-made pretied ligature loop was used to ligate en bloc the pedicles of the hepatic lobes to be resected. A self-made sterile elastic specimen retrieval bag facilitated extraction of the resected liver tissue. In group HEP, the same liver lobes were resected by ligation of their pedicles after midline laparotomy.<br />Results: The percentage of resected liver parenchyma did not differ between groups. All animals returned to normal feeding activity by 48 h postoperation and had no complications.<br />Conclusions: A simple, cost-effective, safe, and efficient laparoscopic technique for 70% partial hepatectomy in the rat was described.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1095-8673
- Volume :
- 205
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Journal of surgical research
- Publication Type :
- Academic Journal
- Accession number :
- 27664874
- Full Text :
- https://doi.org/10.1016/j.jss.2016.06.100