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Radical nerve dissection for the carcinoma of head of pancreas: report of 30 cases.
- Source :
-
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu [Chin J Cancer Res] 2016 Aug; Vol. 28 (4), pp. 429-34. - Publication Year :
- 2016
-
Abstract
- Objective: To explore the clinical value of the radical nerve dissection (RND) for the carcinoma of head of pancreas (CHP).<br />Methods: The clinical and pathological data of 30 CHP patients who underwent RND in our hospital were retrospectively analyzed, with an attempt to explore the safety and short-term efficacy of this procedure.<br />Results: Among these 30 patients, the operative time was (351±61) min, the intra-operative blood loss was 350 (range, 300-600) mL, and the grades B and C pancreatic fistula was 23.33%. During the follow-up (range, 2-30 months; median: 17 months), the 1-year survival rate was 63.33% and the 1-year disease-free survival rate was 56.67%. Among the 23 patients (76.66%) with positive extra-pancreatic perineural invasion (PNI), the 1-year casefatality rate was 34.78%, which was not significantly different from that (28.57%) of patients with negative PNI (P=0.760).<br />Conclusions: Our results suggested potential advantages of RND in the fields of surgery-associated risk and prognosis compared with the Whipple operation in the treatment of CHP. Due to the low sample size of this study, further well-designed research of large sample size is needed.<br />Competing Interests: The authors have no conflicts of interest to declare.
Details
- Language :
- English
- ISSN :
- 1000-9604
- Volume :
- 28
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
- Publication Type :
- Academic Journal
- Accession number :
- 27647971
- Full Text :
- https://doi.org/10.21147/j.issn.1000-9604.2016.04.06