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Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata.
- Source :
-
Natural products and bioprospecting [Nat Prod Bioprospect] 2016 Oct; Vol. 6 (5), pp. 233-237. Date of Electronic Publication: 2016 Sep 19. - Publication Year :
- 2016
-
Abstract
- Four hitherto unknown prenylated coumarins, namely 6″-O-β-D-apiofuranosylapterin (1), 4'-O-isobutyroylpeguangxienin (2), 6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin (3), and 6-hydroxycoumurrayin (4), were isolated from the ethanol extract of Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata, respectively. Their chemical structures were established on the basis of extensive spectroscopic analysis. Compound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480) with IC <subscript>50</subscript> values ranging from 15.9 to 23.2 μM.<br />Competing Interests: The authors declare no conflict of interest.
Details
- Language :
- English
- ISSN :
- 2192-2195
- Volume :
- 6
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Natural products and bioprospecting
- Publication Type :
- Academic Journal
- Accession number :
- 27646268
- Full Text :
- https://doi.org/10.1007/s13659-016-0107-5