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Palladium-Catalyzed Regioselective C-Benzylation via a Rearrangement Reaction: Access to Benzyl-Substituted Anilines.

Authors :
Amézquita-Valencia M
Alper H
Source :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Nov 14; Vol. 22 (47), pp. 16774-16778. Date of Electronic Publication: 2016 Oct 10.
Publication Year :
2016

Abstract

An unprecedented C-benzylation rearrangement reaction, catalyzed by palladium, is reported. The reaction proceeds by rearrangement leading to the direct synthesis of para or ortho benzyl-substituted N-methylanilines. The product is obtained in high regioselectivity, without the need to use a ligand for the catalytic process.<br /> (© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-3765
Volume :
22
Issue :
47
Database :
MEDLINE
Journal :
Chemistry (Weinheim an der Bergstrasse, Germany)
Publication Type :
Academic Journal
Accession number :
27617396
Full Text :
https://doi.org/10.1002/chem.201603941