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Modelling ADHD: A review of ADHD theories through their predictions for computational models of decision-making and reinforcement learning.

Authors :
Ziegler S
Pedersen ML
Mowinckel AM
Biele G
Source :
Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2016 Dec; Vol. 71, pp. 633-656. Date of Electronic Publication: 2016 Sep 05.
Publication Year :
2016

Abstract

Attention deficit hyperactivity disorder (ADHD) is characterized by altered decision-making (DM) and reinforcement learning (RL), for which competing theories propose alternative explanations. Computational modelling contributes to understanding DM and RL by integrating behavioural and neurobiological findings, and could elucidate pathogenic mechanisms behind ADHD. This review of neurobiological theories of ADHD describes predictions for the effect of ADHD on DM and RL as described by the drift-diffusion model of DM (DDM) and a basic RL model. Empirical studies employing these models are also reviewed. While theories often agree on how ADHD should be reflected in model parameters, each theory implies a unique combination of predictions. Empirical studies agree with the theories' assumptions of a lowered DDM drift rate in ADHD, while findings are less conclusive for boundary separation. The few studies employing RL models support a lower choice sensitivity in ADHD, but not an altered learning rate. The discussion outlines research areas for further theoretical refinement in the ADHD field.<br /> (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1873-7528
Volume :
71
Database :
MEDLINE
Journal :
Neuroscience and biobehavioral reviews
Publication Type :
Academic Journal
Accession number :
27608958
Full Text :
https://doi.org/10.1016/j.neubiorev.2016.09.002