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De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence.

Authors :
Sengupta M
Das I
Chatterjee U
Majumdar B
Source :
Journal of oral and maxillofacial pathology : JOMFP [J Oral Maxillofac Pathol] 2016 May-Aug; Vol. 20 (2), pp. 304-7.
Publication Year :
2016

Abstract

Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain.

Details

Language :
English
ISSN :
0973-029X
Volume :
20
Issue :
2
Database :
MEDLINE
Journal :
Journal of oral and maxillofacial pathology : JOMFP
Publication Type :
Report
Accession number :
27601827
Full Text :
https://doi.org/10.4103/0973-029X.185911