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Age-Related Differences in 1- and 12-Month Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation (from a Large Multicenter Data Repository).
- Source :
-
The American journal of cardiology [Am J Cardiol] 2016 Oct 01; Vol. 118 (7), pp. 1024-30. Date of Electronic Publication: 2016 Jul 28. - Publication Year :
- 2016
-
Abstract
- Scarce data are available on the impact of age on transcatheter aortic valve implantation (TAVI) outcomes. We therefore, analyzed 1,845 consecutive patients from 9 Italian centers who underwent TAVI with the Corevalve Revalving System from September 2007 to March 2014; patients were dichotomized according to their age in the date of the procedure, as follows: 75 to 85 years old and >85 years old. End points were defined according to Valve Academic Research Consortium definitions. In-hospital, 30-day, and 1-year clinical and echocardiographic data were available for 100% of the patients included. Propensity matching was performed. Procedural success rates were high (>94%) and comparable between groups. Although worse baseline renal function was observed in the older group, the incidence of acute kidney injury after procedure was comparable (17.1% and 17.4%, respectively for the 75- to 85- and >85-year-old group, p = 0.877); importantly, >99% of acute kidney injury episodes in both groups were grades 1 and 2. Procedural complications rates were low without between-group differences. In-hospital death (3.7% and 4.6%, p = 0.379) and stroke/transient ischemic attack (1.9% and 1.9%, respectively, p = 0.960) were comparable. The 1-year death rates were 14.9% and 17.2% (p = 0.197) in the 75- to 85- and >85-year-old group, respectively. Cardiovascular death was observed in 7.8% and 7% (p = 0.542), while stroke/transient ischemic attack was demonstrated in 5.2% and 4.4% (p = 0.496), respectively. Results were sustained after propensity matching. In conclusion, advanced age did not negatively impact the outcomes of TAVI through 1-year after procedure.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Age Factors
Aged
Aged, 80 and over
Aortic Valve Stenosis diagnostic imaging
Aortic Valve Stenosis epidemiology
Cause of Death
Databases, Factual
Echocardiography
Female
Humans
Incidence
Italy epidemiology
Male
Propensity Score
Renal Insufficiency, Chronic epidemiology
Severity of Illness Index
Treatment Outcome
Acute Kidney Injury epidemiology
Aortic Valve Stenosis surgery
Ischemic Attack, Transient epidemiology
Mortality
Postoperative Complications epidemiology
Stroke epidemiology
Transcatheter Aortic Valve Replacement
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1913
- Volume :
- 118
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The American journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 27561192
- Full Text :
- https://doi.org/10.1016/j.amjcard.2016.07.018