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Regioselective Iodine-Catalyzed Construction of Polysubstituted Pyrroles from Allenes and Enamines.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2016 Sep 16; Vol. 81 (18), pp. 8653-8. Date of Electronic Publication: 2016 Sep 02. - Publication Year :
- 2016
-
Abstract
- A novel I2-catalyzed tandem Michael addition/oxidative annulation of allenes and enamines for the construction of polysubstituted pyrroles has been developed. This protocol represents an efficient and highly regioselective way to access functionalized pyrroles in moderate to excellent yields under mild conditions.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 81
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 27559822
- Full Text :
- https://doi.org/10.1021/acs.joc.6b01737