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Liver resection morbidity, mortality, and risk factors at the departments of hepatobiliary surgery in Veracruz, Mexico.

Authors :
Martínez-Mier G
Esquivel-Torres S
Alvarado-Arenas RA
Ortiz-Bayliss AB
Lajud-Barquín FA
Zilli-Hernandez S
Source :
Revista de gastroenterologia de Mexico [Rev Gastroenterol Mex] 2016 Oct - Dec; Vol. 81 (4), pp. 195-201. Date of Electronic Publication: 2016 Aug 12.
Publication Year :
2016

Abstract

Introduction: Liver resection has been associated with high morbidity and mortality, and the most serious complication is liver failure. Patient evaluation is limited to risk scales. The 50-50 criteria and bilirubin peak>7mg/dl have been used as mortality predictors.<br />Aim: The aim of this study was to determine the risk factors associated with morbidity and mortality for liver resection in our population.<br />Material and Methods: A retrospective study was carried out on 51 patients that underwent liver resection. Sociodemographic variables, pathology, and the surgical act were analyzed, together with morbidity and mortality and their associated factors.<br />Results: Fifty-one patients, 23 men and 28 women, were analyzed. They had a mean age of 51.4±19.13 years, 64.7% had concomitant disease, and their mean MELD score was 7.49±1.79. The mean size of the resected lesions was 7.34±3.47cm, 51% were malignant, and 34 minor resections were performed. The Pringle maneuver was used in 64.7% of the cases and the mean blood loss was 1,090±121.76ml. Morbidity of 25.5% was associated with viral hepatitis infection, greater blood loss, transfusion requirement, the Pringle maneuver, lower hemoglobin and PTT values, and higher MELD, INR, bilirubin, and glucose values. A total 3.9% mortality was associated with hyperbilirubinemia, hyperglycemia, and greater blood loss and transfusions.<br />Conclusions: The main risk factors associated with the morbidity and mortality of liver resection in our population were those related to the preoperative biochemical parameters of the patient and the factors that occurred during the surgical act.<br /> (Copyright © 2016 Asociación Mexicana de Gastroenterología. Publicado por Masson Doyma México S.A. All rights reserved.)

Details

Language :
English; Spanish; Castilian
ISSN :
0375-0906
Volume :
81
Issue :
4
Database :
MEDLINE
Journal :
Revista de gastroenterologia de Mexico
Publication Type :
Academic Journal
Accession number :
27527529
Full Text :
https://doi.org/10.1016/j.rgmx.2016.05.002